Hydrochloric Acid → HCID 178441777, compound

Participants

Reaction Steps

A mixture of the product of Example 18 (117 mg), potassium hydroxide (31.6 mg), ethanol (1.14 ml) and water (253 μl) were stirred at room temperature for 18 h prior to acidification to pH 4 (2N HCl). The resultant mixture was extracted into ethyl acetate (3×10 ml) and the combined organic phases dried and concentrated in vacuo to afford the title compound (73 mg) as a white solid.

Provenance & Evidence