Methyl 3,5-Dihydroxybenzoate → 3,5-Bis[3-(1,1'-biphenyl-3-yloxy)propoxy]benzoic acid methyl ester

HRID 1492831Notes

Reaction equation

HRID 1492831 reaction equation
[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[C:6]([OH:11])[CH:5]=1.Br[CH2:14][CH2:15][CH2:16][O:17][C:18]1[CH:19]=[C:20]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:21]=[CH:22][CH:23]=1>>[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:5]=[C:6]([O:11][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:19]=[C:20]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH:21]=[CH:22][CH:23]=2)[CH:7]=[C:8]([O:10][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:19]=[C:20]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH:21]=[CH:22][CH:23]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 75076Methyl 3,5-DihydroxybenzoateHCID 106849613-Biphenylyl 3-bromopropyl ether

Product 1

HCID 542730643,5-Bis[3-(1,1'-biphenyl-3-yloxy)propoxy]benzoic acid methyl ester

Procedure

Using this procedure, the reaction of 3,5-dihydroxybenzoic acid methyl ester with 3-(3-bromopropoxy)-1,1-biphenyl gave 3,5-bis[3-(1,1'-biphenyl-3-yloxy)propoxy]benzoic acid methyl ester as an oil. The structure was confirmed by nmr and mass spectra.

Sources & evidence

ORD record
ord-8e7129373d2540ea96eab6d066ed8126
Source dataset
uspto-grants-1994_12
Patent number
US05374772

Reaction notes

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