反应详情

A solution of 1.6 g (3.15 mmol) of 3,5-bis[2-[2-(naphthalenyloxy) ethoxy]benzoic acid methyl ester and 15 mL (15 mmol) of 1N NaOH in 45 mL of methanol and 20 mL of dioxane was stirred at reflux for 2 hours. The usual workup followed by recrystallization from THF-ethyl acetate gave 1.2 g (77% yield, mp 205°-207°) of 3,5-bis[2-[2-(naphthalenyloxy)ethoxy]benzoic acid.

1. temperatureat reflux for 2 hours
2. customThe usual workup followed by recrystallization from THF-ethyl acetate