HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → 3-[[6-(2,3-Dihydroxyphenyl) hexyl]oxy]-5-(octadecyloxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | HCID 15233477 | HCID 15233477 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-[[6-(2,3-Dihydroxyphenyl) hexyl]oxy]-5-(octadecyloxy)benzoic acid | HCID 9851628 | 88% |
Reaction Steps
A mixture of 2.0 g of 3-[[6-[2,3-bis(phenylmethoxy)phenyl]hexyl]oxy]-5-(octadecyloxy)benzoic acid phenylmethyl ester and 0.5 g of 10% palladium on carbon in 100 ml of THF was stirred in a hydrogen atmosphere until uptake ceased after 5 hours. The usual workup followed by trituration of the crude product with hexane gave 1.2 g (88% yield, mp 92°-94°) of 3-[[6-(2,3-dihydroxyphenyl) hexyl]oxy]-5-(octadecyloxy)benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05374772 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-6596376abaa74586b267c53086a3b0e3 |
| Source note | uspto-grants-1994_12 |