Sodium Hydroxide → HCID 15233480, compound

HRID 1492842Notes

Reaction equation

[OH-].[Na+].C[O:4][C:5](=[O:46])[C:6]1[CH:11]=[C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:9]=[C:8]([O:31][CH2:32][CH2:33][CH2:34][O:35][C:36]2[CH:41]=[CH:40][C:39]([S:42]([CH3:45])(=[O:44])=[O:43])=[CH:38][CH:37]=2)[CH:7]=1>>[CH3:45][S:42]([C:39]1[CH:38]=[CH:37][C:36]([O:35][CH2:34][CH2:33][CH2:32][O:31][C:8]2[CH:7]=[C:6]([CH:11]=[C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:9]=2)[C:5]([OH:46])=[O:4])=[CH:41][CH:40]=1)(=[O:43])=[O:44]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 15233466HCID 15233466, compound

Product 1

HCID 15233480HCID 15233480, compoundYield 77%

Procedure

Sodium hydroxide hydrolysis of 3-[3-[4-(methylsulfonyl) phenoxy]propoxy]-5-(octadecyloxy)benzoic acid methyl ester as in earlier Examples gave 3-[3-[4-(methylsulfonyl)phenoxy]propoxy]-5-(octadecyloxy)benzoic acid (77% yield, mp 110°-111°).

Sources & evidence

ORD record: ord-81377f4efc5b4799949c1d34d162b852
Source dataset: uspto-grants-1994_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05374772

Reaction notes

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