HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15233467, compound → HCID 15233468, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15233467 | HCID 15233467 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15233468 | HCID 15233468 | 51.2% |
Reaction Steps
A mixture of 0.40 g of 3-(octadecyloxy)-5-[3-[4-(phenylmethoxy) phenoxy]propoxy]benzoic acid methyl ester and 0.1 g of 10% palladium on carbon in 25 ml of THF was stirred in a hydrogen atmosphere for 4 hours. The usual workup followed by purification by chromatography on 12 g of silica gel (230-400 mesh) using 20% ethyl acetate-hexane to give 0.177 g (51% yield, mp 85°-88°) of 3-[3-(4-hydroxyphenoxy)propoxy]-5-(octadecyloxy)benzoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05374772 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-abb087305042402cb4638e4c67024fd6 |
| Source note | uspto-grants-1994_12 |