Acetone → HCID 15233469, compound

Participants

Reaction Steps

A mixture of 1 g (2.4 mmol) of 2-hydroxy-5-(octadecyloxy) benzoic acid methyl ester, 0.85 g (2.6 mmol) of 3-[(4-phenylmethoxy)phenoxy]propyl bromide and 0.65 g (4.7 mmol) of potassium carbonate in 40 ml of acetone and 7 ml of DMF was stirred at reflux for 48 hours. The usual workup followed by recrystallization from ethyl acetate-hexane gave 1.2 g (76% yield, mp 81°-83°) of 5-(octadecyloxy)-2-[3-[4-(phenylmethoxy)phenoxy]propoxy]benzoic acid methyl ester.

Provenance & Evidence