HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Decyloxy)-5-[[6-[2,3-bis(phenylmethoxy)phenyl]hexyl]oxy]benzoic acid → 3-(Decyloxy)-5-[[6-(2,3-dihydroxyphenyl)hexyl]oxy]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Decyloxy)-5-[[6-[2,3-bis(phenylmethoxy)phenyl]hexyl]oxy]benzoic acid | HCID 18951571 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(Decyloxy)-5-[[6-(2,3-dihydroxyphenyl)hexyl]oxy]benzoic acid | HCID 18951548 | 91.1% |
Reaction Steps
A mixture of 1.7 g of 3-(decyloxy)-5-[[6-[2,3-bis(phenylmethoxy) phenyl]hexyl]oxy]benzoic acid and 0.3 g of 10% palladium on carbon in 75 ml of THF was stirred in a hydrogen atmosphere until uptake ceased after 2.5 hours. The usual workup followed by trituration of the crude product from hexane and filtration gave 1.13 g (91% yield, mp 86°-88°) of 3-(decyloxy)-5-[[6-(2,3-dihydroxyphenyl)hexyl]oxy]benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05374772 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-4d75744e6d434bbdb433974fdc7deddb |
| Source note | uspto-grants-1994_12 |