HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15227696, compound → HCID 131718817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15227696 | HCID 15227696 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 131718817 | HCID 131718817 | 112.8% |
Reaction Steps
A mixture of tetraethyl 3-(4-pyridylthio)propylaminomethylenebisphosphonate (7.4 g) and concentrated hydrochloric acid (50 ml) was heated under reflux for 2 hours, and then concentrated under reduced pressure. The residual crystals were collected by filtration to obtain 3-(4-pyridylthio)propylaminomethylenebisphosphonic acid hemihydrate (4.3 g, 77%), and recrystallized from water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05376647 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-15837df2f0fc4f24b3ae420d4e3ac96a |
| Source note | uspto-grants-1994_12 |