HCID 9999611, compound → HCID 135527032, compound

HRID 1493025Notes

Reaction equation

HRID 1493025 reaction equation
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([C:22]2[N:26]=[C:25]([CH3:27])[O:24][N:23]=2)[CH:8]=[C:9]([C:18]([CH3:21])([CH3:20])[CH3:19])[C:10]=1[O:11]COCCOC)([CH3:4])[CH3:3]>[Br-].[Zn+2].[Br-]>[CH3:4][C:2]([C:5]1[CH:6]=[C:7]([C:22]2[N:26]=[C:25]([CH3:27])[O:24][N:23]=2)[CH:8]=[C:9]([C:18]([CH3:21])([CH3:20])[CH3:19])[C:10]=1[OH:11])([CH3:1])[CH3:3]

Participants

3

Reactant 1

HCID 9999611HCID 9999611, compound

Product 1

HCID 135527032HCID 135527032, compoundYield 48%

Reagents, catalysts & solvents 1

HCID 10421208Zinc bromideCatalyst

Procedure

In a manner analogous to Example 59, 2.6 g (0.007 mole) of 3-[3,5-bis(1,1-dimethylethyl)-4-[(2-methoxyethoxy)methoxy]phenyl]-5-methyl-1,2,4-oxadiazole is reacted with 7.7 g (0.03 mole) of zinc bromide to give 0.94 g (48%) of 2,6-bis(1,1-dimethylethyl)-4-(5-methyl-1,2,4-oxadiazol-3-yl)-phenol; mp 126°-127° C.

Sources & evidence

ORD record
ord-e3b85a7406f1485fa6165a0b623ef7b7
Source dataset
uspto-grants-1994_12
Patent number
US05376670

Reaction notes

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