HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-Dichloro-3-oxoindan-1-carbonyl chloride → 4-(5,6-Dichloro-3-oxoindan-1-carbonyl)-3-(piperidinomethyl)thiomorpholine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-Dichloro-3-oxoindan-1-carbonyl chloride | HCID 15132407 | — |
| Reactant | 3-(Piperidinomethyl)thiomorpholine | HCID 18915121 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 4-(5,6-Dichloro-3-oxoindan-1-carbonyl)-3-(piperidinomethyl)thiomorpholine hydrochloride | HCID 18914988 | 34.1% |
Reaction Steps
The procedure described in Example 24 was repeated, but using 0.9 g of 3-(piperidinomethyl)thiomorpholine, 1.0 g of triethylamine and 1.5 g of 5,6-dichloro-3-oxoindan-1-carbonyl chloride to afford 0.45 g of the title compound, melting at 146°-155° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05021413 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-9e6ece0e84b94acf92e7ecf895b0c66d |
| Source note | uspto-grants-1991_06 |