HCID 178510931, compound → HCID 178523906, compound

HRID 1493330Notes

Reaction equation

HRID 1493330 reaction equation
[C:1]([N:9]=[C:10]1[NH:14][CH2:13][CH:12]([CH2:15][O:16][C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([CH2:23][N:24]3[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]3)[CH:18]=2)[O:11]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:30]1[CH:34]=[C:33]([CH2:35][CH2:36][CH2:37][NH2:38])[N:32]=[CH:31]1>N1C=CC=CC=1>[C:1]([NH:9][C:10]([NH:14][CH2:13][CH:12]([OH:11])[CH2:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH2:23][N:24]2[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]2)[CH:18]=1)=[N:38][CH2:37][CH2:36][CH2:35][C:33]1[N:32]=[CH:31][NH:30][CH:34]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 178510931HCID 178510931, compoundHCID 178522539HCID 178522539, compound

Product 1

HCID 178523906HCID 178523906, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

1.97 g (5 mmol) of 2-benzoylimino-5-[(3-piperidinomethylphenoxy)methyl]oxazolidine and 0.69 g (5.5 mmol) of 3-(imidazol-4-yl)propylamine are together heated under reflux in 30 ml of pyridine for 8 hours. The solvent is distilled off under vacuum, and the reaction product is isolated and purified by a method analogous to Method A.

Workup

  1. distillationThe solvent is distilled off under vacuum
  2. customthe reaction product is isolated
  3. custompurified by a method analogous to Method A

Sources & evidence

ORD record
ord-2f9acf80baef401c9944a2f22da1f89f
Source dataset
uspto-grants-1991_06
Patent number
US05021431

Reaction notes

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