Diisopropylamine → 4-Benzimidazol-1-yl-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester

HRID 149349Notes

Reaction equation

HRID 149349 reaction equation
[CH:37]([NH:38][CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[Cl:1][C:2](=[O:3])[O:4][c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:9][cH:10]1.[NH:22]1[CH2:23][CH2:24][CH:25]([n:28]2[cH:29][n:30][c:31]3[c:32]2[cH:33][cH:34][cH:35][cH:36]3)[CH2:26][CH2:27]1>>[C:2](=[O:3])([O:4][c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:9][cH:10]1)[N:22]1[CH2:23][CH2:24][CH:25]([n:28]2[cH:29][n:30][c:31]3[c:32]2[cH:33][cH:34][cH:35][cH:36]3)[CH2:26][CH2:27]1

Participants

4

Reactant 3

HCID 7912DiisopropylamineHCID 30192621-(4-Piperidinyl)-1H-benzimidazoleHCID 220477624-(5-Trifluoromethylpyridin-2-yloxy)-phenyl chloroformate

Product 1

HCID 695178894-Benzimidazol-1-yl-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester

Sources & evidence

ORD record
ord-84eec1d2617347c8ab0ca1956c401969
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…