Formic Acid → HCID 19830064, compound

Participants

Reaction Steps

To a solution of 0.35 ml of formic acid in 10 ml of dry chloroform were added 1.5 g of 1,1'-carbonyldiimidazole and 1.74 ml of methyl iodide, and the mixture was stirred at room temperature for 2.5 hours. To the reaction mixture was added a solution of 0.5 g of 3,9-dihydroxy-5H-benzofuro[3,2-c]quinolin-6-one in 10 ml of dry N,N-dimethylformamide, and the mixture was stirred overnight at room temperature. To the reaction mixture was added 30 ml of water, and the precipitates were collected by filtration, washed with ethyl acetate, and dried at 60° C under reduced pressure to obtain 0.54 g of 3,9-bis(formyloxy)-5H-benzofuro[3,2-c]quinolin-6-one.

Provenance & Evidence