Water → HCID 14819622, compound

Participants

Reaction Steps

In 15 ml of dry N,N-dimethylformamide was suspended 500 mg of 3,9-dihydroxy-5H-benzofuro[3,2-c]quinolin-6-one. To the suspension were added 0.55 ml of methyl isocyanate and 1.7 ml of triethylamine, and the mixture was stirred overnight at room temperature. To the reaction mixture were added 0.33 ml of methyl isocyanate and 0.78 ml of triethylamine, and the mixture was poured into 180 ml of water. The precipitates were collected by filtration, washed with ether, and dried under reduced pressure to obtain 593 mg of 3,9-bis(N-methylcarbamoyloxy)-5H-benzofuro[3,2-c]quinolin-6-one.

Provenance & Evidence