Methane → HCID 61506956, compound

Participants

Reaction Steps

A mixture of 4-methoxy-3-methylaniline (5 g, 0.0364 mol), methyl glyoxylate (5.5 g, 0.0619 mol) and palladium over charcoal (3.7 g; 10%) in methanol (300 ml) was stirred under a hydrogen atmosphere for 1 hour. The suspension was filtered through hyflo and evaporated to give a yellow solid. This was triturated with ether at ~-78° C. and filtered to give the title compound as a pale yellow solid (3.8 g, 50%) m.p. 69°-71° C.

Provenance & Evidence