HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1493663Generated: November 2, 2026
HCID 67924073, compound → HCID 67924103, compound
https://huagongshe.com/reaction/1493663
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 67924073 | HCID 67924073 | — |
| Solvent | Lithium Hydroxide | HCID 3939 | — |
| Solvent | Diglyme | HCID 8150 | — |
| Product | HCID 67924103 | HCID 67924103 | 69.1% |
Reaction Steps
A mixture of 14α-carbethoxymethyl-5α-cholest-8-en-3β-ol (100 mg) in diglyme (3 mL) and 1N lithium hydroxide (3 mL) was heated at 130° C. for 2 hours under argon. The cooled reaction was partitioned between methylene chloride and iced dilute HCl, and the dried and concentrated organic layer provided 65 mg of 14α-carboxymethyl-5α-cholest-8-en-3β-ol; mp 191°-193° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05023250 |
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| Source dataset | uspto-grants-1991_06 |
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| ORD ID | ord-65ea5db19d79496e9e3118fa638929f5 |
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| Source note | uspto-grants-1991_06 |
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