Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 14996561 | HCID 14996561 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | Cefadroxil hemihydrate | HCID 67173987 | 87.7% |
Reaction Steps
Cefadroxil monomethylformamide solvate (30 g) prepared according to Example 3 was slurried in 150 ml of a mixture 1:1 of methanol and isopropyl alcohol at 52° C. After 70' at 52° C. the mixture was cooled to 10° C., filtered and washed with acetone to yield 23.2 g of crystalline cefadroxil hemihydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05023331 |
|---|
| Source dataset | uspto-grants-1991_06 |
|---|
| ORD ID | ord-3c384e2a56364745ba7eddb6b383525b |
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| Source note | uspto-grants-1991_06 |
|---|
