反应详情

A mixture of 3.63 gm (0.03 mole) of 4-acetylpyridine, 4.51 gm (0.03 mole) of o-toluic acid hydrazide and 100 ml of 95% ethanol is refluxed 8 hr. The hot solution is filtered. The filtrate is diluted with water to the cloud point and cooled to room temperature. The mixture is chilled in the refrigerator and the product collected, washed with water, and dried to yield 4.78 gm (63%) of the title compound having a melting point of 187.4° C.

1. temperatureis refluxed 8 hr
2. filtrationThe hot solution is filtered
3. additionThe filtrate is diluted with water to the cloud point
4. temperatureThe mixture is chilled in the refrigerator
5. customthe product collected
6. washwashed with water
7. customdried