Hydrazinecarboxylic acid, ethyl ester → HCID 4179285, compound

HRID 1493702Notes

Reaction equation

HRID 1493702 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=O)=[CH:3][CH:2]=1.[CH2:15]([O:17][C:18](=[O:21])[NH:19][NH2:20])[CH3:16]>C(O)(=O)C>[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:20][NH:19][C:18]([O:17][CH2:15][CH3:16])=[O:21])[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 267314-Benzoylpyridine

Product 1

HCID 4179285HCID 4179285, compoundYield 42.8%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 9.16 gm (0.05 mole) of phenyl 4-pyridyl ketone, 5.21 gm (0.05 mole) of ethylcarbazate and 75 ml of glacial acetic acid is heated at 100° C. for 8 hr. The acetic acid is removed in vacuo. The residue is slurried with ethyl ether and collected to yield 5.76 gm (39%) of the title compound having a melting point of 188.7° C.

Workup

  1. customThe acetic acid is removed in vacuo
  2. customcollected

Sources & evidence

ORD record
ord-974284088fd24d11960c0dcfabfea584
Source dataset
uspto-grants-1991_06
Patent number
US05023334

Reaction notes

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