Ethanol → Cyclohexanecarboxylic acid [1-(4-pyridinyl)ethylidene]hydrazide 1-oxide

Participants

Reaction Steps

A mixture of 5.48 gm (0.04 mole) of 4-acetylpyridine 1-oxide, 5.68 gm (0.04 mole) of cyclohexanecarboxylic acid hydrazide and 100 ml of absolute ethanol is refluxed 4 hours. The reaction mixture is concentrated in vacuo to dryness to give a solid. The solid is crystallized from isopropanol to furnish 8.20 gm (79%) of the title compound; mp 245.3°.

Provenance & Evidence