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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1493726Generated: October 31, 2026

HCID 15623023, compound → Ethyl 4-(6-acetyl-3-hydroxy-2-propylphenoxy)butanoate

https://huagongshe.com/reaction/1493726

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 15623023HCID 15623023—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductEthyl 4-(6-acetyl-3-hydroxy-2-propylphenoxy)butanoateHCID 1562302470.5%

Reaction Steps

A solution of ethyl 4-(6-acetyl-3-benzyloxy-2-propylphenoxy)butanoate (2.2 g) in ethanol (30 ml) was hydrogenated over 10% palladium on activated carbon (0.45 g) under atmospheric pressure at room temperature. After hydrogen absorption ceased, the catalyst was removed and the solution was evaporated. The residue was purified by silica gel column chromatography, eluting with benzene-ethyl acetate (1:4), to give the title compound (1.2 g, 70.5%) as yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05023364
Source datasetuspto-grants-1991_06
ORD IDord-929a54ef47db44a0821a12e3c6ea3462
Source noteuspto-grants-1991_06