HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15623023, compound → Ethyl 4-(6-acetyl-3-hydroxy-2-propylphenoxy)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15623023 | HCID 15623023 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 4-(6-acetyl-3-hydroxy-2-propylphenoxy)butanoate | HCID 15623024 | 70.5% |
Reaction Steps
A solution of ethyl 4-(6-acetyl-3-benzyloxy-2-propylphenoxy)butanoate (2.2 g) in ethanol (30 ml) was hydrogenated over 10% palladium on activated carbon (0.45 g) under atmospheric pressure at room temperature. After hydrogen absorption ceased, the catalyst was removed and the solution was evaporated. The residue was purified by silica gel column chromatography, eluting with benzene-ethyl acetate (1:4), to give the title compound (1.2 g, 70.5%) as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05023364 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-929a54ef47db44a0821a12e3c6ea3462 |
| Source note | uspto-grants-1991_06 |