Water → HCID 14346530, compound

Participants

Reaction Steps

Solid potassium carbonate (1.94 g) was added at room temperature to a solution of the product from stage (i) (1 g) in dry dimethylformamide. Benzyl bromide (2.41 g) was added. The mixture was stirred overnight. Ice and water were added. The mixture was extracted with ether. The extracts were washed with water, dried and evaporated. The oil obtained was purified by FCC using ether/hexane (1:1) as eluent, to give the title compound as a yellow oil which crystallised slowly (1.82 g) m.p. 44°-47.5°.

Provenance & Evidence