Hydrochloric Acid → HCID 14346541, compound

Participants

Reaction Steps

A solution of the product from Stage (iii) (10 g) and 2N sodium hydroxide (50 ml) in ethanol (50 ml) was heated under reflux for 30 min. The solution was cooled, poured into water, acidified with 2N hydrochloric acid and extracted with ether. The extracts were dried and evaporated and the residue purified by FCC using hexane/ether (7:3) as eluent. The product was crystallised from hexane to give the title compound (4.2 g) as a white solid, m.p. 73°-74°.

Provenance & Evidence