HRID1493867

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID98094

3-Amino-N-ethylpiperidine

C7H16N2

结构：CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)Oc1ccccc1)OC

HCID15101201

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)NC1CCCN(CC)C1)OC

HCID54565188

未命名化合物

CONDITIONS

反应条件

温度: 60 °C

PROCEDURE

实验过程

3-Amino-1-ethylpiperidine (1 ml) was added to 1.3 g of 1-octadecylcarbamoyl-2-methyl-3-phenoxycarbonylglycerol, and the reaction solution was heated at 60° C. for 1 hour and purified by silica gel chromatography [ethyl acetate-methanol (10:1)] to give 1.13 g of the objective compound as a milk-white solid.

WORKUP

后处理

custompurified by silica gel chromatography [ethyl acetate-methanol (10:1)]

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6f1e74cb3e364a17866e9f32432eaeba
来源数据集: uspto-grants-1991_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05025005
来源说明: uspto-grants-1991_06

反应 SMILES

[NH2:1][CH:2]1[CH2:7][CH2:6][CH2:5][N:4]([CH2:8][CH3:9])[CH2:3]1.[CH2:10]([NH:28][C:29]([O:31][CH2:32][CH:33]([CH2:36][O:37][C:38](OC1C=CC=CC=1)=[O:39])[O:34][CH3:35])=[O:30])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>>[CH2:10]([NH:28][C:29]([O:31][CH2:32][CH:33]([CH2:36][O:37][C:38](=[O:39])[NH:1][CH:2]1[CH2:7][CH2:6][CH2:5][N:4]([CH2:8][CH3:9])[CH2:3]1)[O:34][CH3:35])=[O:30])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]