HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromoanisole → 3-(4-Phenyl-1H-imidazol-1-yl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromoanisole | HCID 16971 | — |
| Reactant | 3-(1H-Imidazol-1-yl)phenol | HCID 10464591 | — |
| Reactant | HCID 178418822 | HCID 178418822 | — |
| Product | 3-(4-Phenyl-1H-imidazol-1-yl)phenol | HCID 12718443 | 57% |
Reaction Steps
Following the procedure for preparation of 3-(1H-imidazol-1-yl)phenol (preparation 7), 4-phenylimidazole (20 g, 0.138 mole) and 3-bromoanisole (32 ml, 0.25 mole) were reacted to give the title compound in 57% yield, mp 195°-197° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05025031 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-527304fd518e43ea806bf616536622c4 |
| Source note | uspto-grants-1991_06 |