2-Naphthol → 2-(2-Naphthyloxy)propanedioic acid diethyl ester

Participants

Reaction Steps

This compound was prepared following Procedure 33. Thus, a mixture of 43.2 g (0.3 mole) of 2-naphthol, 70 g (0.36 mole) of diethylchloromalonate and 69.1 g (0.5 mole) of anhydous potassium carbonate in 750 ml of acetone gave 84.0 g (93%) of a tan solid. An analytical sample, mp 57°-58.5° C. (lit.1 mp 57°-58° C.), was recrystallized from isopropyl ether.

Provenance & Evidence