2-(Benzyloxy) ethanol → HCID 19108681, compound

HRID 1493984Notes

Reaction equation

HRID 1493984 reaction equation
[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[CH2:6]([O:13][CH2:14][CH2:15][OH:16])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[C:7]1([CH2:6][O:13][CH2:14][CH2:15][O:16][S:1](=[O:4])(=[O:3])[NH2:2])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 121412-(Benzyloxy) ethanolHCID 24499Chlorosulfamic acid

Product 1

HCID 19108681HCID 19108681, compound

Procedure

The title compound was prepared by procedures of Example 16 from sulfamoyl chloride and 2-(benzyloxy)ethanol except the oil obtained was then further purified by high pressure chromatography as described in earlier examples using methylene chloride as the eluting agent. Fractions containing the title compound were combined and the solvent was evaporated under reduced pressure to give title compound in 54% yield as light-yellow, viscous oil.

Workup

  1. customobtained
  2. customwas then further purified by high pressure chromatography
  3. additionFractions containing the title compound
  4. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-8b1195a6da67428c80f1931154beb24a
Source dataset
uspto-grants-1991_06
Patent number
US05025031

Reaction notes

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