Chlorosulfonyl isocyanate → HCID 15229163, compound

HRID 1494007Notes

Reaction equation

HRID 1494007 reaction equation
Cl[S:2]([N:5]=C=O)(=[O:4])=[O:3].[OH:8][C:9]1[CH:10]=[C:11]([CH:16]=[CH:17][CH:18]=1)[C:12]([O:14][CH3:15])=[O:13]>C1(C)C=CC=CC=1>[CH3:15][O:14][C:12]([C:11]1[CH:10]=[C:9]([O:8][S:2](=[O:3])(=[O:4])[NH2:5])[CH:18]=[CH:17][CH:16]=1)=[O:13]

Participants

4

Reactant 2

HCID 70918Chlorosulfonyl isocyanateHCID 88068Methyl 3-Hydroxybenzoate

Product 1

HCID 15229163HCID 15229163, compoundYield 45.5%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Following the procedure of Example 50, a reaction of 8.8 ml (0.10 mole) chlorosulfonyl isocyanate and 15.2 g (0.10 mole) of methyl 3-hydroxybenzoate in 200 ml of toluene was heated at reflux for 7.5 hr and worked up to obtain 10.53 g of solid, mp 145°-146° C.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 7.5 hr

Sources & evidence

ORD record
ord-c994f79d66b4476ab8db89da6fa6d956
Source dataset
uspto-grants-1991_06
Patent number
US05025031

Reaction notes

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