HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 14986665, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-Carbomethoxy-8-(3-pyridyl)-oct-7-enenitrile | HCID 54396583 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 14986665 | HCID 14986665 | — |
Reaction Steps
A mixture of 8.7 g of 5-carbomethoxy-8-(3-pyridyl)-oct-7-enenitrile and 4.35 g of 5% rhodium on alumina in 87 mL of methanol saturated with ammonia (7.4N) is hydrogenated at room temperature for about 6 hours. Additional catalyst is added if required. The reaction mixture is then worked up to yield methyl 6-amino-2-[3-(3-pyridyl)propyl]hexanoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05025025 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-d15068e4b5784ba6813eeba53366b6b3 |
| Source note | uspto-grants-1991_06 |