Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 10250599 | HCID 10250599 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 10066486 | HCID 10066486 | — |
Reaction Steps
A mixture of 0.12 g (0.3 mmol) ethyl 8-methanesulfonyloxy-4-[3-(3-pyridyl)propyl]-3-thia-octanoate, 1.5 mL dimethylformamide and 0.062 g (0.95 mmol) sodium azide is heated at 60° C. for 18 hours. The mixture is then poured into water and extracted with ether. The organic phase is washed with water, saturated brine, dried, filtered and evaporated to give ethyl 8-azido-4-[3-(3-pyridyl)propyl]-3-thia-octanoate; IR (CH2Cl2) 2099, 1732 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05025025 |
|---|
| Source dataset | uspto-grants-1991_06 |
|---|
| ORD ID | ord-44ba01edddcb480492c53983b3fa4ec4 |
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| Source note | uspto-grants-1991_06 |
|---|
