Sodium Hydroxide → HCID 10388467, compound

HRID 1494134Notes

Reaction equation

HRID 1494134 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:16]([CH2:23][CH2:24][CH2:25][C:26]2[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=2)[CH2:17][C:18]([O:20]CC)=[O:19])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[OH-].[Na+]>CO>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:16]([CH2:23][CH2:24][CH2:25][C:26]2[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=2)[CH2:17][C:18]([OH:20])=[O:19])(=[O:9])=[O:10])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 10027569HCID 10027569, compound

Product 1

HCID 10388467HCID 10388467, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrolysis of ethyl 7-(p-chlorophenylsulfonamido)-3[3-(3-pyridyl)propyl]heptanoate in 3 mL methanol with 5.2 mL (5.2 mmol) of 1N sodium hydroxide according to procedure described in the previous examples yields 7-(p-chlorophenylsulfonamido)-3-[3-(3-pyridyl)propyl]heptanoic acid, m.p. 95-97°.

Sources & evidence

ORD record
ord-7b8c8a54463a450994ec6ac7e6114aeb
Source dataset
uspto-grants-1991_06
Patent number
US05025025

Reaction notes

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