HuagongsheHuagongshe Chemistry Print Report · For research reference only
Swainsonine → Hexahydro-1H-pyrrolizine-1,2,6,7-tetraol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Swainsonine | HCID 51683 | — |
| Reactant | d-Glycero-d-talo-heptono-1,4-lactone | HCID 95162420 | — |
| Product | Hexahydro-1H-pyrrolizine-1,2,6,7-tetraol | HCID 14683616 | — |
Reaction Steps
The tetrahydroxypyrrolizidone (1) is an analogue of 1,8-diepiswainsonine. A similar analogue of swainsonine can be made by analogous methods starting with D-glycero-D-talo-heptono-1,4-lactone to produce the novel (1S), 2R, 6R, 7S)-1,2,6,7-tetrahydroxypyrrolizidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05025098 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-af2dc18516984b5cb0d9ec46a058d3a1 |
| Source note | uspto-grants-1991_06 |