4-[6-[2,3-Bis(phenylmethoxy)phenyl]hexyloxy]benzoic acid ethyl ester → 4-[6-(2,3-Dihydroxyphenyl)hexyloxy]benzoic acid ethyl ester

Participants

Reaction Steps

A solution of 2.3 g of 4-[6-[2,3-bis(phenylmethoxy)phenyl]hexyloxy]benzoic acid ethyl ester in 50 mL of ethyl acetate and 0.3 g of 10% palladium on carbon was stirred in a hydrogen atmosphere for 22 hours. The reaction mixture was filtered through Celite and the filtrate was concentrated under reduced pressure to a solid. Recrystallization from ethyl acetate-hexane gave 1.3 g, mp 45°-47°, (85% yield) to 4-[6-(2,3-dihydroxyphenyl)hexyloxy]benzoic acid ethyl ester.

Provenance & Evidence