Benzoyl chloride, 3-nitro- → HCID 16876476, compound

HRID 1494295Notes

Reaction equation

HRID 1494295 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7](Cl)=[O:8])([O-:3])=[O:2].[CH3:13][O:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1.[Cl-].[Al+3].[Cl-].[Cl-]>C(Cl)Cl>[CH3:13][O:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][C:16]=1[C:7]([C:6]1[CH:10]=[CH:11][CH:12]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)=[O:8]

Participants

5

Reactant 3

HCID 8495Benzoyl chloride, 3-nitro-HCID 90161,4-DimethoxybenzeneHCID 6451240Aluminum(III) Chloride

Product 1

HCID 16876476HCID 16876476, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

In a 3 l-volume three-necked flask were charged 372 g of m-nitrobenzoyl chloride and 280 g of p-dimethoxybenzene, and 1.6 l of methylene chloride were added thereto to form a solution. To the solution were added dropwise 300 g of aluminum chloride over about 1 hour while stirring at room temperature. The reaction mixture slightly generated heat, and the methylene chloride began to reflux. After stirring was continued for about 2 hours, the reaction mixture was allowed to stand overnight.

Workup

  1. additionwere added
  2. customto form a solution
  3. temperatureThe reaction mixture slightly generated heat
  4. temperatureto reflux
  5. stirringAfter stirring
  6. waitto stand overnight

Sources & evidence

ORD record
ord-0b146a207c234ee49f1177ca93c563da
Source dataset
uspto-grants-1991_06
Patent number
US05026634

Reaction notes

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