Oxalic acid dihydrate → HCID 19827809, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.9 g (3.1 mmol) N-cyclohexyl-2-amino-4-nitroaniline and 1.0 g (7.9 mmol) oxalic acid dihydrate in 50 ml 4 N hydrochloric acid was refluxed for 5 h. After cooling to 25° C. the product was filtered off. The crude product was recrystallized (ether-water) to give 0.2 g (19%) 1-cyclohexyl-6-nitroquinoxaline-2,3(1H,4H)-dione. M.p. (DSC): decomp. 1H-NMR (DMSO-d6): 12.2 (1H, broad s), 8.1-7.7 (3H, m), 3.0-1.0 (11H, m).

Provenance & Evidence