Potassium Nitrate → HCID 19827808, compound

HRID 1494325Notes

Reaction equation

HRID 1494325 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]([CH3:13])[C:8](=[O:14])[C:7](=[O:15])[NH:6]2.[N+:16]([O-])([O-:18])=[O:17].[K+]>S(=O)(=O)(O)O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[N+:16]([O-:18])=[O:17])[N:9]([CH3:13])[C:8](=[O:14])[C:7](=[O:15])[NH:6]2

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 19827790HCID 19827790, compound

Product 1

HCID 19827808HCID 19827808, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

To a solution of 0.2 g (0.97 mmol) 6-methoxy-1-methylquinoxaline-2,3(1H,4H)-dione in 10 ml concentrated sulfuric acid was added at 0° C. 0.1 g (0.99 mmol) potassium nitrate. Stirring was continued at 0° C. for 30 min., and then at 25° C. for 1 h. The reaction mixture was poured into 50 ml ice-water to give a precipitate Recrystallization (dimethylformamide-water) of the crude product gave 0.15 g (62%) 6-methoxy-1-methyl-7-nitroquinoxaline-2,3(1H,4H)-dione. M.p. 356° C. NMR (DMSO-d6): 12.0 (1H, broad s), 7.77 (1H, s), 3.90 (3H, s), 3.47 (3H, s).

Workup

  1. waitat 25° C. for 1 h
  2. customto give
  3. customa precipitate Recrystallization (dimethylformamide-water) of the crude product

Sources & evidence

ORD record
ord-177a97e3269c47d5bb2622db491cfbfa
Source dataset
uspto-grants-1991_06
Patent number
US05026704

Reaction notes

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