Potassium Nitrate → HCID 19827813, compound

HRID 1494341Notes

Reaction equation

HRID 1494341 reaction equation
[CH:1]1([N:7]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([Cl:17])[CH:15]=3)[NH:10][C:9](=[O:18])[C:8]2=[O:19])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[N+:20]([O-])([O-:22])=[O:21].[K+]>S(=O)(=O)(O)O>[CH:1]1([N:7]2[C:16]3[C:11](=[CH:12][C:13]([N+:20]([O-:22])=[O:21])=[C:14]([Cl:17])[CH:15]=3)[NH:10][C:9](=[O:18])[C:8]2=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 19827791HCID 19827791, compound

Product 1

HCID 19827813HCID 19827813, compoundYield 84.2%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

A solution of 3.1 g (11 mmol) 1-cyclohexyl-7-chlorquinoxaline-2,3(1H,4H)-dione in 100 ml concentrated sulfuric acid (95-97%) was ice-cooled and then added 1.1 g (11 mmol) potassium nitrate. Stirring was continued at 0° C. for 30 min. and then at 25° C. for 17 h. The reaction mixture was poured into 500 ml ice-water. The precipitate was filtered off and washed with water to give 3.0 g (82%) 1-cyclohexyl-6-nitro-7-chlorquinoxaline-2,3(1H,4H)-dione. M.p. (DSC): decomp. 1H-NMR (DMSO-d6): 12.2 (1H, broad s), 7.9 (2H, s), 4.0-1.0 (11H, m).

Workup

  1. temperaturecooled
  2. waitat 25° C. for 17 h
  3. filtrationThe precipitate was filtered off
  4. washwashed with water

Sources & evidence

ORD record
ord-9aadc9d7eab942aeba833f8dea78613c
Source dataset
uspto-grants-1991_06
Patent number
US05026704

Reaction notes

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