2-Methylimidazole → HCID 13810558, compound

HRID 1494366Notes

Reaction equation

HRID 1494366 reaction equation
ClCCCC([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[NH:13][S:14]([CH3:17])(=[O:16])=[O:15])=O.[CH3:18][C:19]1[NH:20][CH:21]=[CH:22][N:23]=1>>[CH3:18][C:19]1[N:23]2[CH2:9][CH2:8][CH:7]=[C:12]([C:11]3[CH:12]=[CH:7][C:8]([NH:13][S:14]([CH3:17])(=[O:15])=[O:16])=[CH:9][CH:10]=3)[C:22]2=[CH:21][N:20]=1

Participants

3

Reactant 2

HCID 127492-MethylimidazoleHCID 11161699HCID 11161699, compound

Product 1

HCID 13810558HCID 13810558, compound

Procedure

Combine 100 g (0.36 mol) of N-[(4-chloro-l-oxobutyl)phenyl] methanesulfonamide with 400 g (4.88 mol) of 2-methylimidazole and heat to 175° C. for 22 hr under argon. Crystallization from methylene chloride provides the title compound.

Workup

  1. customCrystallization from methylene chloride

Sources & evidence

ORD record
ord-f02a0fced87a4883a28633ebc32c7991
Source dataset
uspto-grants-1991_06
Patent number
US05026712

Reaction notes

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