[1-[4-[2-(6-Amino-8-bromopurin-9-yl)ethyl]piperidin-1-yl]-1-oxopropan-2-yl] acetate → [1-[4-[2-[6-Amino-8-[(7-chloro-1,3-benzothiazol-2-yl)sulfanyl]purin-9-yl]ethyl]piperidin-1-yl]-1-oxopropan-2-yl] acetate
Reaction equation
[C:1]([CH3:2])(=[O:3])[O:4][CH:5]([C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][CH2:15][n:16]2[c:17]3[n:18][cH:19][n:20][c:21]([NH2:26])[c:22]3[n:23][c:24]2[Br:25])[CH2:12][CH2:13]1)[CH3:27].[Cl:28][c:29]1[cH:30][cH:31][cH:32][c:33]2[n:34][c:35]([SH:38])[s:36][c:37]12>>[C:1]([CH3:2])(=[O:3])[O:4][CH:5]([C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][CH2:15][n:16]2[c:17]3[n:18][cH:19][n:20][c:21]([NH2:26])[c:22]3[n:23][c:24]2[S:38][c:35]2[n:34][c:33]3[cH:32][cH:31][cH:30][c:29]([Cl:28])[c:37]3[s:36]2)[CH2:12][CH2:13]1)[CH3:27]Participants
3
Sources & evidence
- ORD record
- ord-5b79c750e14b482dbaca71547716bfaf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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