N-bromobutanimide → HCID 13810561, compound

HRID 1494373Notes

Reaction equation

HRID 1494373 reaction equation
[CH3:1][C:2]1[N:6]2[CH:7]=[CH:8][CH:9]=[C:10]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH:21]=[CH:20][N:19]=[C:18]4[CH3:22])=[CH:13][CH:12]=3)[C:5]2=[CH:4][N:3]=1.[Br:23]N1C(=O)CCC1=O>C(Cl)Cl>[Br:23][C:4]1[N:3]=[C:2]([CH3:1])[N:6]2[CH:7]=[CH:8][CH:9]=[C:10]([C:11]3[CH:12]=[CH:13][C:14]([N:17]4[CH:21]=[CH:20][N:19]=[C:18]4[CH3:22])=[CH:15][CH:16]=3)[C:5]=12

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 13764030HCID 13764030, compound

Product 1

HCID 13810561HCID 13810561, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Combine 2.2 g (7.6 mmol) of the product of Example XIV with 1.4 g (7.9 mmol) of N-bromosuccinimide in 50 ml of methylene chloride and stir at room temperature for 1 hr. Wash the reaction with 100 ml of 10% potassium carbonate solution, dry over magnesium sulfate, treat with charcoal, and remove the solvent in vacuo. Crystallize the residue from ether to provide the title compound.

Workup

  1. washWash
  2. customthe reaction with 100 ml of 10% potassium carbonate solution
  3. dry with materialdry over magnesium sulfate
  4. additiontreat with charcoal
  5. customremove the solvent in vacuo
  6. customCrystallize the residue from ether

Sources & evidence

ORD record
ord-1cb9849a777343bbb675c9c6cf136fe4
Source dataset
uspto-grants-1991_06
Patent number
US05026712

Reaction notes

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