Methyl iodide → HCID 13536439, compound

Participants

Reaction Steps

50 mmol of propyl 4-(2-chlorophenyl)-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro-[3,4-b]pyridine-3-carboxylate are dissolved in 150 ml of dimethyl sulphoxide, and 7 g of potassium hydroxide powder and 50 mmol of methyl iodide are added. After 2 hours at room temperature, the mixture is poured onto ice-water and extracted with CH2Cl2, the extract is dried and evaporated down, and the residue is recrystallized.

Provenance & Evidence