Ethanol → HCID 641388, compound

HRID 1494580Notes

Reaction equation

HRID 1494580 reaction equation
[SH:1][C:2]1[S:3][C:4]([SH:7])=[N:5][N:6]=1.[CH2:8]1[O:10][CH2:9]1.[CH2:11]([OH:13])[CH3:12]>>[OH:13][CH2:11][CH2:12][S:1][C:2]1[S:3][C:4]([S:7][CH2:9][CH2:8][OH:10])=[N:5][N:6]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 6354Ethylene OxideHCID 178418558HCID 178418558, compound

Product 1

HCID 641388HCID 641388, compound

Procedure

2,5-Dimercapto-1,3,4-thiadiazole(80.6 grams, 0.54 moles) and ethanol (150 ml) were charged into reaction flask and stirred. The flask was flushed with nitrogen and then ethylene oxide (54 grams, 1.3 moles) was added slowly via a gas inlet directly above the surface of the solution. The reaction mixture was refluxed with stirring for 15 minutes. The solvent was stripped off by using a rotary evaporator at approximately 20 mm Hg and 100° C. The product was a white solid and characterized by infrared absorption bands at 3350, 2900, 1675, 1385, 1285, 1050, 750, and 710 cm-1.

Workup

  1. customThe flask was flushed with nitrogen
  2. temperatureThe reaction mixture was refluxed
  3. stirringwith stirring for 15 minutes
  4. customa rotary evaporator at approximately 20 mm Hg and 100° C
  5. customcharacterized by infrared absorption bands at 3350, 2900, 1675, 1385, 1285, 1050, 750, and 710 cm-1

Sources & evidence

ORD record
ord-bc3554434a154ce19945406f2f5d231e
Source dataset
uspto-grants-1991_06
Patent number
US05026865

Reaction notes

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