2,3-Dihydroxybutanedioic Acid → HCID 15086836, compound

HRID 1494593Notes

Reaction equation

HRID 1494593 reaction equation
[NH2:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][C:9]1[NH:10][C:11]([CH3:32])=[C:12]([C:28]([O:30][CH3:31])=[O:29])[CH:13]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[C:21]=2[Cl:27])[C:14]=1[C:15]([O:17][CH2:18][CH3:19])=[O:16].[C:33]([OH:42])(=[O:41])[CH:34]([CH:36]([C:38]([OH:40])=[O:39])[OH:37])[OH:35]>>[C:38]([CH:36]([CH:34]([C:33]([OH:42])=[O:41])[OH:35])[OH:37])([OH:40])=[O:39].[NH2:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][C:9]1[NH:10][C:11]([CH3:32])=[C:12]([C:28]([O:30][CH3:31])=[O:29])[CH:13]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[C:21]=2[Cl:27])[C:14]=1[C:15]([O:17][CH2:18][CH3:19])=[O:16]

Participants

3

Reactant 2

HCID 8752,3-Dihydroxybutanedioic AcidHCID 1315323-Ethyl 5-methyl 2-{[2-(2-aminoethoxy)ethoxy]methyl}-4-(2,3-dichlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Product 1

HCID 15086836HCID 15086836, compound

Procedure

0.2 g of the compound of Example 50 is dissolved in 3.1 ml of a 0.133M ethanolic solution of (+)-tartaric acid. After evaporation of the solvent, 0.24 g of the expected salt is obtained.

Workup

  1. customAfter evaporation of the solvent

Sources & evidence

ORD record
ord-6d93c1b8de774e7ead4e66201b41e42f
Source dataset
uspto-grants-1991_06
Patent number
US05026863

Reaction notes

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