Bromine → HCID 19828696, compound

HRID 1494598Notes

Reaction equation

HRID 1494598 reaction equation
[CH:1]([C:3]1([C:12](=[O:14])[CH3:13])[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4]1)=[CH2:2].[Br:15]Br>C(Cl)Cl>[Br:15][CH2:13][C:12]([C:3]1([CH:1]=[CH2:2])[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4]1)=[O:14]

Participants

4

Reactant 2

HCID 24408BromineHCID 19828702HCID 19828702, compound

Product 1

HCID 19828696HCID 19828696, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

1-(2,3-Dihydro-2-vinyl-1H-inden-2-yl)-ethanone (5.0 g) was dissolved in methylene chloride (50 ml) and to the solution bromine (4.3 g) in methylene chloride (45 ml) was added dropwise at room temperature. When a gas chromatogram indicated that the starting material had reacted, the methylene chloride solution was washed with a dilute NaHCO3 -solution and then with water. The organic layer was dried with Na2SO4 and the solvent was evaporated at reduced pressure to give the desired product.

Workup

  1. additionwas added dropwise at room temperature
  2. customhad reacted
  3. washthe methylene chloride solution was washed with a dilute NaHCO3 -solution
  4. dry with materialThe organic layer was dried with Na2SO4
  5. customthe solvent was evaporated at reduced pressure

Sources & evidence

ORD record
ord-762043a9144e4535925a3171f0415f02
Source dataset
uspto-grants-1991_06
Patent number
US05026868

Reaction notes

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