HuagongsheHuagongshe Chemistry Print Report · For research reference only
Swainsonine → (1S,2R,6R,7S)-1,2,6,7-tetrahydroxypyrrolizidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Swainsonine | HCID 51683 | — |
| Reactant | d-Glycero-d-talo-heptono-1,4-lactone | HCID 95162420 | — |
| Product | (1S,2R,6R,7S)-1,2,6,7-tetrahydroxypyrrolizidine | HCID 10313338 | — |
Reaction Steps
The tetrahydroxypyrrolizidone (1) is an analogue of 1,8-diepiswainsonine. A similar analogue of swainsonine can be made by analogous methods starting with D-glycero-D-talo-heptono-1,4-lactone to produce the novel (1S, 2R, 6R, 7S)-1,2,6,7-tetrahydroxypyrrolizidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05026870 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-88e800e4448042938511a78f3389dedb |
| Source note | uspto-grants-1991_06 |