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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1494727Generated: October 31, 2026

1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 14795757, compound

https://huagongshe.com/reaction/1494727

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 535414—
Reactant4-methoxy-2,3-dihydro-1H-isoindoleHCID 14795864—
SolventDimethylformamideHCID 6228—
ProductHCID 14795757HCID 1479575766.7%

Reaction Steps

136 mg of 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 224 mg of 4-methoxyisoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 2 to produce 132 mg of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05026856
Source datasetuspto-grants-1991_06
ORD IDord-930e9d1c5bfe4b648e6280d400bd411b
Source noteuspto-grants-1991_06