HuagongsheHuagongshe Chemistry Print Report · For research reference only
8,9-Difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid → HCID 15167915, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8,9-Difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid | HCID 534278 | — |
| Reactant | 2,3-Dihydro-1H-isoindol-5-amine | HCID 14795862 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 15167915 | HCID 15167915 | 56.2% |
Reaction Steps
157 mg of 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid, 242 mg of 5-aminoisoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 2 to produce 124 mg of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05026856 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-7cc314f27d354f99b0aedc68715bcbdd |
| Source note | uspto-grants-1991_06 |