HuagongsheHuagongshe Chemistry Print Report · For research reference only
8,9-Difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid → HCID 15167918, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8,9-Difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid | HCID 534278 | — |
| Reactant | 4-fluoro-2,3-dihydro-1H-isoindole | HCID 14795867 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 15167918 | HCID 15167918 | 35.5% |
Reaction Steps
141 mg of 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid, 206 mg of 4-fluoroisoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 71 mg of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05026856 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-d78c24f1b921487db803a4ad1a9ab777 |
| Source note | uspto-grants-1991_06 |