HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid → HCID 14795818, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | HCID 13728330 | — |
| Reactant | 4-bromo-2,3-dihydro-1H-isoindole | HCID 14795870 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 14795818 | HCID 14795818 | 62.4% |
Reaction Steps
170 mg of 1-(4-fluorophenyl)-6,7,8-trifluoro-1,4- dihydro-4-oxoquinoline-3-carboxylic acid, 300 mg of 4-bromoisoindoline, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 20 to produce 162 mg of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05026856 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-8ebac60599ce4a18b03079b0b7ebbd14 |
| Source note | uspto-grants-1991_06 |